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Fluphenazine occurs as typical antipsychotic drug. It belongs to the piperazine-class of phenothiazines. These are extremly potent (50 to 70-days a potency of chlorpromazine). Fluphenazine is possibly somewhat other potent than haloperidol. These are utilized for the coarse of action of psychoses like schizophrenia and acute manic phases of bipolar depression.

Pharmacokinetics
Fluphenazine has an uncomplete unwritten bioavailability of 40% to 50% (due to extensive number one pass metabolization in the liver). Its half life is 15 to 30 hours.

Side effects
Usual come extrapyramidal side effects, including tardive dyskinesia. A frequency & hardship of extrapyramidal side results come straight proportional to a dose given & the duration of professional assistance.

More side results (sedation, hypotension, anticholinergic effects like xerostomia, blurred vision etc.) as well alter by having a dose given.

As a member of the thiodiphenylamine class of doses, fluphenazine shares generally completely side-results of chlorpromazine. Sedative drug, allergic-toxic & anticholinergic/sympatholytic side effects come less probably to occur equated sustaining thorazine. A straight deposition of fluphenazine in the cornea and retina has so far non been reported.

Brand names
Fluphenazine decanoate: Modecate®, Prolixin Decanoate®, Dapotum D®, Anatensol®, Fludecate®, Sinqualone deconoat®.

Fluphenazine enanthate: Dapotum Injektion®, Flunanthate®, Moditen Enanthate Injection®, Sinqualone Enantat®.

Fluphenazine hydrochloride: Prolixin®, Permitil®, Dapotum®, Lyogen®, Lyogen®, Moditen®, Omca®, Sediten®, Selecten®, Sevinol®, Siqualone®, Trancin®.

Prolixin and Permitil
Full prescribing information from RxList.

Fluphenazine - Familydoctor.org
Information for patients in English and Spanish.

Fluphenazine Decanoate
Internet Mental Health page discusses pharmacology, indications and contraindications, precautions, dosage, and other topics. From a Canadian monograph.
Health: Pharmacy: Drugs and Medications: Antipsychotics






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